The Mass Spectrometry Unit consists of three gas chromatograph-mass spectrometers (GC/MS); two liquid chromatograph-mass spectrometers (LC/MS); three liquid chromatograph-tandem mass spectrometers (LC/MS/MS); an isotope ratio mass spectrometer (IRMS) an inductive-coupled plasma mass spectrometer (ICP-MS); and a new high resolution quadrupole-time of flight tandem mass spectrometer (QTOF).
The GC/MS, LC/MS and LC/MS/MS instruments are used for quantification and identification of vitamins, amino acids, nucleic acids, lipids, fatty acids, retinoids, carotenoids, antioxidants, peptides, and proteins from food and human body fluids. The IRMS is used for measuring C-13 carbon dioxide in breath. The ICP-MS is use for determinations of trace metals in biological fluids. The QTOF will be used for lipidomics, metabolomics and proteomics. Data generated by these instruments are the primary outcomes in many human nutrition, aging and exercise studies.
Gregory G. Dolnikowski, Ph.D.
Manager, Scientist I
Provides managerial and scientific direction to the laboratory, and he teaches scientific personnel to use GC/MS, LC/MS and LC/MS/MS methods in research protocols.
Meghan Faherty, B.S., Administrative Coordinator