Biostatistics and Data Management Unit

The Biostatistics and Data Management Scientific Core Unit assists research teams with biostatistics, bioinformatics, and data management.  The core unit works with investigators on study design, implementation, and data analysis to support research activities across basic science, animal, and human studies in nutrition, with an emphasis on rigor, reproducibility and transparency.

The core unit supports development of statistical analysis plans to ensure appropriate data analysis methods, proper handling of missing data and multiple testing issues, and appropriately powered studies.  Special care is taken to address statistical issues that arise in nutrition studies, such as selection of appropriate control diets and minimization of measurement error.   The core unit provides bioinformatics support for targeted and untargeted metabolomics, machine learning approaches (random forest and neural networks), genomic and metagenomics sequencing, and integrative omics analyses.

The core unit assists investigators with implementation, monitoring and adherence to data management plans (adhering to NIH and USDA requirements) including electronic data capture (REDCap and LabArchives) as well as clinical trials registration and summary results submission to ClinicalTrials.gov per the Final Rule issued by the U.S. DHHS and the NIH.  Support is provided for the creation, maintenance, and archival of databases that meet all federal requirements.

We welcome partnering with HNRCA investigators on biostatistics and data management needs. See the HNRCA Biostatistics and Data Management Core Services table which lists the services available and indicates whether they are HNRCA-supported services (no cost recovery) or services provided through cost recovery.

Staff

Marcus Lehr, MS, Senior Data Analyst
Fred Nusetor, MS, Biostatistician
Josh Rutt, Ph.D., Associate Director for Biostatistics and Data Management
Emilie Buisson, MSc, Data Management Specialist