The long-term objective of this project is to enhance scientific knowledge on the physiological benefits of increased vitamin K consumption in order to develop more precise vitamin K intake recommendations.
1. To characterize dietary factors, including food composition and nutrient-nutrient interactions, and non-dietary factors, such as genetics, that contribute to the inter-individual variation in vitamin K intake, bioavailability, and utilization and vitamin K metabolite production.
2. Determine the role(s) and mechanism(s) of action for vitamin K beyond its essential role in coagulation, including the role of vitamin K in the prevention of abnormal non-skeletal calcification and the mechanisms of vitamin K action not currently explained by its role as an enzyme cofactor.
Sarah Booth, Ph.D., Laboratory Director Interim HNRCA Center Director, Senior Scientist
Research focus: vitamin K status and chronic disease, bioavailability, food composition
Xueyan Fu, Ph.D. Scientist II
Research focus: vitamin K bioavailability and role of vitamin K in inflammation and insulin resistance
Kyla Shea, Ph.D.
Research focus: understanding the role of vitamin K in age-related disease
Jessica Ellis, M.S., Graduate Research Assistant Meghan Faherty, M.S./M.P.H., Senior Research Administrator Jennifer Kelly, R.D., M.S., Graduate Research Assistant Xiaohua Shen, M.D., Research Assistant