Current Research Projects • USDA-ARS: Cardiovascular Nutrition and Health
Biography Dr. Nirupa Matthan is Scientist I in the Cardiovascular Nutrition Laboratory at the HNRCA. Her research interests include heart disease and lifestyle risk factors with specific emphasis on objective biomarkers of diet quality and endogenous metabolism. Dr. Matthan also has expertise in the measurement of cholesterol absorption and synthesis markers, lipoprotein kinetics following dietary modification and targeted lipidomics. Recent projects address the role of carbohydrate and fat type on heart disease risk factors, glycemic index, fatty acid metabolism using stable isotopes, the relationship between plasma biomarkers of nutrient intake and diet quality in a family based weight management program, and the effect of avocado consumption on changes in fat in overweight and obese Americans. Past projects include human metabolic studies on trans fatty acids, soy protein and isoflavones, and novel vegetable oils differing in fatty acid profile on heart disease risk. Dr. Matthan’s most recent research involves the feasibility and safety of a soy-based diet for pregnant women and establishing the Ossabaw miniature pig as a translational model to study diet-drug interactions on atherosclerosis development, a disease characterized by the deposition of fats on the inner walls of the arteries. She is Assistant Professor at the Friedman School of Nutrition Science and Policy and Faculty Senator in the Tufts University Faculty Senate. Dr. Matthan chairs the Tufts University-wide faculty senate committee on research and scholarship. She has several professional affiliations, including the American Heart Association (Council on Lifestyle and Cardiometabolic Health), American Society for Nutrition, and Boston Nutrition Obesity Research Center.