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The purpose of this study is to determine whether long-term intake of a modified form of Isoquercitrin, called Enzymatically Modified Isoquercitrin (EMIQ), a natural plant product, safely decreases total body fat and body weight in obese and overweight individuals, compared to a placebo.

Target Population
Men and women ages 18 to 65 years old

Major Exclusions
• BMI < 26 and > 37 kg/m2
• Smoking
• Diabetes, kidney or heart disease, rheumatoid arthritis
• Alcohol consumption of 14 or more drinks per week
• Pregnant or breastfeeding
• Weigh less than 164lbs

Length of Study
12 weeks


Number of visits
1 screening visit, 5 study visits for collection of blood, urine, and clinical information (i.e., blood pressure and weight), electrocardiogram (EKG), resting metabolic rate (RMR), and dual energy x-ray absorptiometry (DXA) measurements

Study diet
Isoquercitrin supplements will be provided during the 12-week study period

Can I work?

$25 for screening, and an additional stipend of up to $605 for participants who qualify and complete the entire study.

Length of study

Total length of the study including resident stays and nonresident visits.
This does not mean you will be testing the entire time.

The length of time volunteers are required to stay overnight at the HNRCA. Residents have their own private room, bathroom, television, VCR, and phone during their stay.

The amount of reimbursement for travel and inconvenience.
Number of visits

Total number of nonresident visits.
Study diet

Indicates meals which will be provided by the HNRCA
Can I work?

Indicates if you will be able to work and if so, when.

For more information about this study, please call Volunteer Services at 1-800-738-7555 .

We appreciate your interest in our program and we hope to work with you in the future.

Thank you,
The Recruitment Office
Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University