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The purpose of this research study is to determine how the two fatty acids present in fish and fish oil, called EPA and DHA, affect cardiovascular disease risk factors with a specific emphasis on inflammation, triglycerides and cholesterol.

Target Population
Men and postmenopausal women aged 50-74 years old

Major Exclusions
• Allergies to fish, fish oil or shellfish
• Smoking in the last 6 months
• Diabetes, kidney or liver disease
• Anticoagulants (blood thinners), aspirin, NSAIDs (non-steroidal anti-inflammatory drugs), hormone therapy (estrogen), steroids
• High fish intake (>2 servings of fish per week)
• Consuming omega-3 supplements (fish oil, cod liver oil, flaxseed, etc.)
• Alcohol consumption of more than 7 drinks per week
• Vegetarians/vegans

Length of Study
34 weeks


Study diet
Throughout the rest of the study, volunteers will follow a standardized diet (the “TLC diet”) on their own for the entire length of the study (34 weeks). Instructions will be provided by a dietitian. Volunteers will be required to consume up to 4 capsules a day (2 in the morning and 2 in the evening).

$20 for the 1st screening visit, $25 for the 2nd screening visit, and up to $980 for participants who qualify and complete the entire study.

Can I work?

Length of study

Total length of the study including resident stays and nonresident visits.
This does not mean you will be testing the entire time.

The length of time volunteers are required to stay overnight at the HNRCA. Residents have their own private room, bathroom, television, VCR, and phone during their stay.

The amount of reimbursement for travel and inconvenience.
Number of visits

Total number of nonresident visits.
Study diet

Indicates meals which will be provided by the HNRCA
Can I work?

Indicates if you will be able to work and if so, when.

For more information about this study, please call Volunteer Services at 1-800-738-7555 .

We appreciate your interest in our program and we hope to work with you in the future.

Thank you,
The Recruitment Office
Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University