Vitamin K

The long-term objective of this project is to enhance scientific knowledge on the physiological benefits of increased vitamin K consumption in order to develop more precise vitamin K intake recommendations.

Lab Objectives
1. To characterize dietary factors, including food composition and nutrient-nutrient interactions, and non-dietary factors, such as genetics, that contribute to the inter-individual variation in vitamin K intake, bioavailability, and utilization and vitamin K metabolite production.

2. Determine the role(s) and mechanism(s) of action for vitamin K beyond its essential role in coagulation, including the role of vitamin K in the prevention of abnormal non-skeletal calcification and the mechanisms of vitamin K action not currently explained by its role as an enzyme cofactor.

Lab Members
Sarah Booth, Ph.D.
Director, Vitamin K Laboratory
Associate Director, Senior Scientist and Professor, Nutrition
Research focus: vitamin K status and chronic disease, bioavailability, food composition

Xueyan Fu, Ph.D.
Scientist II
Research focus: vitamin K bioavailability and role of vitamin K in inflammation and insulin resistance

Kyla Shea, Ph.D.
Scientist II
Research focus: understanding the role of vitamin K in age-related disease

Xiaohua Shen, MD, Research Assistant
Jessica Ellis, MS, Graduate Research Assistant
Jennifer Kelly, RD, MS, Graduate Research Assistant
Meghan Faherty, MS/MPH., Senior Research Administrator

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