Donald E. Smith, Ph.D., CMAR

Scientist II and Manager
Comparative Biology Unit
711 Washington Street
Boston, MA 02111-1524
Phone: (617) 556-3201
Fax: (617) 556-3344
Education Ph.D., Veterinary Medicine
Hokkaido University, Graduate School of Veterinary Medicine
Research Focus Animal models for dietary/nutritional interventions related to aging and associated degenerative conditions
Academic Appointments Clinical Assistant Professor, Nutrition, Gerald J. and Dorothy R. Friedman School of Nutrition Science and Policy at Tufts University
Selected Professional Affiliations American Association of Laboratory
Animal Sciences
Recent Publications
Liu Z, Ciappio ED, Crott JW, Brooks RS, Nesvet J, Smith DE, Choi SW, Mason JB. Combined inadequacies of multiple B vitamins amplify colonic Wnt signaling and promote intestinal tumorigenesis in BAT-LacZxApc1638N mice.FASEB J. 2011 Sep;25(9):3136-45.Kim KC, Jang H, Sauer J, Zimmerly EM, Liu Z, Chanson A, Smith DE, Friso S, Choi SW. Folate supplementation differently affects uracil content in DNA in the mouse colon and liver. Br J Nutr. 2011 Mar;105(5):688-93.

Crivello NA, Casseus SL, Peterson JW, Smith DE, Booth SL. Age- and brain region-specific effects of dietary vitamin K on myelin sulfatides. J Nutr Biochem. 2010 Nov;21(11):1083-8.

Crivello NA, Blusztajn JK, Joseph JA, Shukitt-Hale B, Smith DE. Short-term nutritional folate deficiency in rats has a greater effect on choline and acetylcholine metabolism in the peripheral nervous system than in the brain, and this effect escalates with age. Nutr Res. 2010 Oct;30(10):722-30.

Chen CY, Crott J, Liu Z, Smith DE. Fructose and saturated fats predispose hyperinsulinemia in lean male rat offspring. Eur J Nutr. 2010 Sep;49(6):337-43.

Sauer J, Jang H, Zimmerly EM, Kim KC, Liu Z, Chanson A, Smith DE, Mason JB, Friso S, Choi SW. Ageing, chronic alcohol consumption and folate are determinants of genomic DNA methylation, p16 promoter methylation and the expression of p16 in the mouse colon. Br J Nutr. 2010 Jul;104(1):24-30.

Mernitz H, Lian F, Smith DE, Meydani SN, Wang XD. Fish oil supplementation inhibits NNK-induced lung carcinogenesis in the A/J mouse. Nutr Cancer. 2009;61(5):663-9.