2790: Pecans and Inflammation Research Study

The purpose of this study is to evaluate the effects of pecans on biomarkers of heart disease and type 2 diabetes risk.  Participants will be asked to consume meals provided by the Center for 8 weeks in total, and have blood and urine samples collected.

Target Population
Men and postmenopausal women age 45 years and older

Major Exclusions
• BMI <25 or >35
• Smoking, vegetarians
• Hormone replacement therapy
• Cholesterol or blood pressure-lowering medications
• Diabetes, kidney or heart disease, rheumatoid arthritis
• Alcohol consumption of 2 or more drinks per day

Length of Study
12 weeks, including a 2 week run-in period before the first diet phase and a 2 week washout period between each diet phase

# of visits
1 screening visit, 5 study visits for collection of blood, urine, and clinical information (i.e., blood pressure and weight), and at least 2 visits each week to pick up prepared meals over a total of 8 weeks


Study diet
For 2 weeks prior to your first study visit, and for the 2 weeks between each diet phase, volunteers will follow an average American diet, low in fruit, vegetables, fiber, with no nuts or nut products.  Instructions will be provided.

All foods and beverages will be provided during each 4 week diet phase (8 weeks in total).

Must stop all dietary supplements, and nut consumption, one month before enrollment.

$25 for screening, and up to $575 for participants who qualify and complete the entire study

Length of study

Total length of the study including resident stays and nonresident visits.
This does not mean you will be testing the entire time.

The length of time volunteers are required to stay overnight at the HNRCA. Residents have their own private room, bathroom, television, VCR, and phone during their stay.

The amount of reimbursement for travel and inconvenience.
Number of visits

Total number of nonresident visits.
Study diet

Indicates meals which will be provided by the HNRCA
Can I work?

Indicates if you will be able to work and if so, when.

For more information about this study, please call Volunteer Services at 1-800-738-7555.

We appreciate your interest in our program and we hope to work with you in the future.

Thank you,
The Recruitment Office
Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University