1542: Fatty Acid & Inflammation/ acid metabolism

Purpose
This research study will determine how diets containing three different types of fatty acids: stearic (found in cocoa butter, meats), palmitic (found in meats, dairy and some plant oils) and oleic (found in olive and corn oil) affect cardiovascular disease risk factors, with a specific emphasis on inflammation.  In addition, the purpose will be to determine how stearic acid and oleic acid are metabolized in the body.

Target Population
Postmenopausal women, ages 50 to 85 years

Major Exclusions
Men
BMI < 20 and > 35 kg/m2
Smoker
Alcohol intake greater than 7 drinks per week
Heart Disease
High blood pressure
Diabetes
Taking medication known to affect lipid metabolism, such as statins

Length of Study
15 weeks (excluding 2-4 week washout period in-between each diet phase)

Residency
Optional. Each phase requires one full-day visit with the option of remaining in the Center overnight.

Study diet
All food and beverages will be provided during the 15-week period.

Stipend
Potential volunteers will receive $20.00 for completing the screening 1 visit, and $25.00 for completing the screening 2 visit to compensate for travel and parking costs.  Additionally, volunteers will receive a total of $2,010 upon completion of the 3 diet phases.

NOTES:
Length of study

Total length of the study including resident stays and nonresident visits.
This does not mean you will be testing the entire time.
Residency

The length of time volunteers are required to stay overnight at the HNRCA. Residents have their own private room, bathroom, television, VCR, and phone during their stay.
Payment

The amount of reimbursement for travel and inconvenience.
Number of visits

Total number of nonresident visits.
Study diet

Indicates meals which will be provided by the HNRCA
Can I work?

Indicates if you will be able to work and if so, when.

For more information about this study, please call Volunteer Services at 1-800-738-7555 or complete our Study Inquiry Form.

We appreciate your interest in our program and we hope to work with you in the future.

Thank you,
The Recruitment Office
Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University